Found 66 matching trials
The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin) PHASE1 To assess the influence of BI 187004 on kinetics of cytochrome P450 (CYP) a...
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1307.19.1 Boehringer Ingelheim Investigational Site
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A Study of Perpetrator Drug Interactions of Enasidenib in AML Patients PHASE1 This is a 2-part, open-label, interventional study conducted in approximate...
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Local Institution - 103
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Drug-drug Interaction Study of Gepotidacin PHASE1 This study is a drug-drug interaction (DDI), pharmacokinetics (PK), safety ...
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GSK Investigational Site
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Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone PHASE1 The purpose of this study is to determine to what extent CYP2B6, CYP3A4, an...
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University of Washington General Clinical Research Center
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A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib PHASE1 This study is being done to look at how tucatinib could affect the way othe...
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Covance Clinical Research Unit
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Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients PHASE1 To study the Pharmacokinetics (PK) parameters of montelukast, flurbiprofen,...
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Multiple Locations
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A Drug-Drug Interaction Study of LY3537982 on Midazolam, Digoxin, and Rosuvastatin in Healthy Participants PHASE1 The main purpose of this study is to evaluate the effects of multiple doses...
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ICON Early Clinical & Bioanalytical Solutions
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A Pharmacokinetic Study to Assess Drug-drug Interaction Between Zanubrutinib and a Cocktail of Substrates in Healthy Subjects PHASE1 This study is designed to evaluate the safety and pharmacokinetic interacti...
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Covance Clinical Research Unit
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A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677 PHASE1 It is a phase 1, open-label, single-center, three-part study to assess the ...
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Richmond Pharmacology Limited
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A Drug Interaction Study of ACH-0145228 PHASE1 This was a 2-part study (Part 1 and Part 2), with each part being an open-l...
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Clinical Study Site
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